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Review Article | OPEN ACCESS

Qualitative analysis of plant-derived samples by liquid chromatography-electrospray ionization-quadrupole-time of flight-mass spectrometry

Yun-Bin Jiang1, Mei Zhong2, Wei Peng1

1College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610075; 2Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 73000, PR China.

For correspondence:-  Wei Peng   Email: pengwei002@126.com

Received: 18 November 2014        Accepted: 10 April 2015        Published: 26 May 2015

Citation: Jiang Y, Zhong M, Peng W. Qualitative analysis of plant-derived samples by liquid chromatography-electrospray ionization-quadrupole-time of flight-mass spectrometry. Trop J Pharm Res 2015; 14(5):925-930 doi: 10.4314/tjpr.v14i5.25

© 2015 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: Currently, mass spectrometry has become an effective method for the qualitative analysis of plant-derived samples. Precursor and product ions can be obtained by tandem mass spectrometry, supplying rich information for determining the structural formulas of compounds. In this work, we review the optimization of qualitative methods using liquid chromatography-electrospray ionization-quadrupole-time of flight (LC-ESI-Q-TOF), coupled with ultraviolet and infrared spectroscopy, nuclear magnetic resonance, and mass spectrometry. This paper provides a systemic reference for researchers engaged in the qualitative analysis of plant-derived samples using LC-ESI-Q-TOF.

Keywords: Qualitative analysis, Liquid chromatography-electrospray ionization-quadrupole-time of flight (LC-ESI-Q-TOF), Mass spectrometry, Optimization

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Thompson Reuters (ISI): 0.523 (2021)
H-5 index (Google Scholar): 39 (2021)

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